doll
Junior Member
Posts: 62
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Post by doll on Apr 5, 2007 8:44:11 GMT -5
Hi everyone! I also posted this on another board I belong to cause I thought it was a pretty interesting read! I tailored it more for gals there, but it's a good read for ALL endo and pain patients in general as many of us know folks who are pain patients have a bit of a belly ;D...even the ones that are thin...INTERESTING huh? It's another new idea about inflammatory conditions. It says that fat cells in the abdomen fuel inflammatory diseases. The full text of the article can be found here: www.sciencedaily.com/releases/2007/03/070313150435.htm============================================= Belly Fat May Drive Inflammatory Processes Associated With Disease Science Daily — As scientists learn more about the key role of inflammation in diabetes, heart disease and other disorders, new research from Washington University School of Medicine in St. Louis suggests that fat in the belly may be an important promoter of that inflammation. Excess fat is known to be associated with disease, but now the researchers have confirmed that fat cells inside the abdomen are secreting molecules that increase inflammation. It's the first evidence of a potential mechanistic link between abdominal fat and systemic inflammation. [..] Reporting in the journal Diabetes, the research team says visceral fat likely contributes to increases in systemic inflammation and insulin resistance. They sampled blood from the portal vein in obese patients undergoing gastric bypass surgery and found that visceral fat in the abdomen was secreting high levels of an important inflammatory molecule called interleukin-6 (IL-6) into portal vein blood. [..] Increased IL-6 levels in the portal vein correlated with concentrations of an inflammatory substance called C-reactive protein (CRP) in the body. High CRP levels are related to inflammation, and chronic inflammation is associated with insulin resistance, hypertension, type 2 diabetes and atherosclerosis, among other things. "These data support the notion that visceral fat produces inflammatory cytokines that contribute to insulin resistance and cardiovascular disease," says Klein. HOPE THIS HELPS SOMEONE! ;D
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Post by angelas on Apr 5, 2007 9:46:16 GMT -5
Uhm... that is very very interesting! I have felt that for the past few months I've been looking like I'm prego cause of the bloating in my abdomen!! The only problem is that it doesn't seem to go down much after my period. My pants all fit the same as they always did, but I can still see it and feel it that its different! I wonder if that will go away after surgery?? or does it just keep growing??
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Post by ouchy on Apr 5, 2007 10:32:38 GMT -5
My bloating (not fat) went down after my surgery, but I had intestinal endometriosis, and I think the bloating was from that in my case.
Hummm. I do have insulin resistance, though! Even when I was skinny, scrawny, apparently (based on my cycles).
Thanks for posting this.
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Post by angelas on Apr 5, 2007 11:10:42 GMT -5
Since bloating is not the same as fat - it would make sense that that would go down. But in my understanding of the article, the fat cells are what is secreting the molecules. Do those fat cells just keep growing then? No matter what?
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Post by ouchy on Apr 5, 2007 11:39:26 GMT -5
I'm not sure I'm understanding. You can control the fat cells by your dietary intake and exercise. I don't read where it says that the fat cells keep growing and growing.
It does make sense, though, that the more visceral belly fat a person has, the more inflammation-producing molecules would be produced and also a higher risk for diabetes and insulin resistance. However, you can also be thin and be insulin resistant, have diabetes, or even have inflammation.
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doll
Junior Member
Posts: 62
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Post by doll on Apr 5, 2007 14:16:28 GMT -5
Yes, one can be thin and have all the inflammation issues. I however, have heard of many gals with endo who are super thin and have the belly fat issue and somehow I know appreciate the article more.
I have the belly endo fat as well. In addition, I GAINED 45 pounds on Lupron! I feel gross and like an absolute PIG! I was NEVER thin, but I felt very comfortable being a size 7. I'm 5'7' and used to weigh 130 pounds and was very attractive.
I have no idea what to do! I've tried eating less and exercising more. I tried going on the protein low carb diet, etc... For a long time (two years) I have been at 175 pounds and basically can;t take it anymore. YES, it was AFTER Lupron! No matter what I have tried in these two years I can't get this damn weight off! I refuse to throw away all my old clothes, but having to purchase size 16 when I was always a 7 is truly depressing.
One thing I will admit and I am ashamed of...I have NEVER done the endo diet. Should I? I mean, would it help me lose 40 pounds or just help with pain? I'd LOVE suggestions! HELP!
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Post by ouchy on Apr 5, 2007 14:46:17 GMT -5
Hey, doll. I did an insulin resistance diet (as the article demonstrates that insulin resistance goes along w/ belly fat), and it also gave me 0 endo pain and 0 blood clots. I guess there may be a connection. Anyway, I was on it for about 1.5 months (have had to quit bc of pregnancy appetite issues), but I can say my tummy trimmed down a LOT! I also lost a quick 10-15 pounds or so after not being able to lose weight at all, no matter what I tried. If you're interested, let me know, and I can recommend a book that puts it all in perspective. (BTW, this is NOT one of those strict, low-carb diets. It balances good carbs w/ protein. Doesn't feel like a diet.) A big part of not being able to lose weight often has to do with insulin resistance. I can identify with gaining weight. I went from 130 to over 200 in a matter of months after starting Ortho Tri-Cyclen and some other issues like not being able to walk (from something else), etc. I lost a LOT by doing pilates and starting to walk again, but I reached a plateau and couldn't seem to lose the rest (until this diet). I also did not know at the time that I was insulin resistant. I know I'm completely rambling in this post, but I also wanted to let you know that I put my husband on the diet after finding out his father and grandmother are diabetic and realizing what my husband's messed-up labs (triglycerides, etc.) was actually pointing to insulin resistance and pre-diabetes. He lost 20 pounds super fast, too, after not being able to lose! BTW, I did appreciate your article.
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doll
Junior Member
Posts: 62
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Post by doll on Apr 5, 2007 16:18:15 GMT -5
Hey, doll. I did an insulin resistance diet (as the article demonstrates that insulin resistance goes along w/ belly fat), and it also gave me 0 endo pain and 0 blood clots. I guess there may be a connection. Anyway, I was on it for about 1.5 months (have had to quit bc of pregnancy appetite issues), but I can say my tummy trimmed down a LOT! I also lost a quick 10-15 pounds or so after not being able to lose weight at all, no matter what I tried. If you're interested, let me know, and I can recommend a book that puts it all in perspective. (BTW, this is NOT one of those strict, low-carb diets. It balances good carbs w/ protein. Doesn't feel like a diet.) A big part of not being able to lose weight often has to do with insulin resistance. I can identify with gaining weight. I went from 130 to over 200 in a matter of months after starting Ortho Tri-Cyclen and some other issues like not being able to walk (from something else), etc. I lost a LOT by doing pilates and starting to walk again, but I reached a plateau and couldn't seem to lose the rest (until this diet). I also did not know at the time that I was insulin resistant. I know I'm completely rambling in this post, but I also wanted to let you know that I put my husband on the diet after finding out his father and grandmother are diabetic and realizing what my husband's messed-up labs (triglycerides, etc.) was actually pointing to insulin resistance and pre-diabetes. He lost 20 pounds super fast, too, after not being able to lose! BTW, I did appreciate your article. First, you are not rambling as what you discuss is great info. also, thanks for the props you gave me. I enjoy passing along interesting articles when I find them. SHARING IS CARING! Next, PLEASE PLEASE recommend the book you posted about, so I can run out and get it. I will try it and when I try something...I stick with it and am devoted and don't cheat. I'd appreciate any suggestions VERY MUCH!
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Post by angelas on Apr 6, 2007 9:18:08 GMT -5
Thanks Ouchy! You answered my seemingly confusing questions also!
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Post by ouchy on Apr 6, 2007 9:22:22 GMT -5
I did? LOL. That's good. Here is a copy/paste of a post I made in another thread re: Syndrome X book. A lot of people w/ insulin resistance also have trouble w/ fertility, so it also recommends another book. "Well, I checked out a book called Syndrome X: The Complete Nutritional Program to Prevent and Reverse Insulin Resistance (Insulin Resistance (IR) caused my hormones to be out-of-whack and for me to either ovulate extremely late or not at all.) Here is a website for that book, but I just checked it out at the library. www.syndrome-x.com/I did my own version of the diet based on the book. And it balanced my hormones the first month, allowing me to ovulate on day 16! <--That was unheard of for me! The diet also made me have 0 menstrual cramps and 0 blood clots, when I thought I was going to have to go for another lap bc the cramps had recently been so bad. If you have a problem with hormones, I recommend that book on Syndrome X. If you are serious about getting pregnant and want to do it as quickly as possible and learn SO much about your body, I HIGHLY recommend the book Denna recently bought, Taking Charge of Your Fertility by Toni Weschler. Here is a link to the author's website. You can buy the book very cheaply on eBay, though. www.tcoyf.com " P.S. You can also get the Syndrome X book on eBay or amazon.
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Post by ouchy on Apr 6, 2007 9:25:11 GMT -5
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Post by angelas on Apr 6, 2007 10:07:31 GMT -5
So did you have to have tests done to see if you are insulin resistant?? I'm just wondering how I could know that without getting the bloodwork done?
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Post by ouchy on Apr 6, 2007 10:45:19 GMT -5
Actually, my OBGYN told me that insulin resistance is a huge factor in PCOS. He told me that the tests for insulin resistance are long, tedious, not always accurate, and he sees some form of insulin resistance in over 90% of his patients w/ PCOS. He gave me a prescription for Metformin (a blood sugar lowering drug), and he told me that if it works, I would most likely have on-time ovulation. The first month I took it, I ovulated day 16 or something (when I would usually ovulate around day 37-42 or something). So, by reducing my sugar, I had normal ovulation. This meant that I was insulin resistant. He said that I'd know within the first couple months whether or not the Metformin worked, and it worked right away.
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Post by angelas on Apr 6, 2007 11:27:00 GMT -5
wow! thats awesome that you were able to figure that out just by taking metformin! I'm guessing that the insulin resistance isn't something I have to worry about right now since I know I don't have PCOS. But I guess when it comes time to conceive I suppose we will be looking at my ovulation cycles... I have no idea if that is on track or not?
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Post by ouchy on Apr 6, 2007 12:05:50 GMT -5
Try BBT charting. It's incredibly simple, and you can learn SO much about what your body is/isn't doing!
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