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Clomid
Dec 25, 2006 19:54:26 GMT -5
Post by ouchy on Dec 25, 2006 19:54:26 GMT -5
Also take in to consideration that a lot of women w/ endo do have other problems that do interfere w/ ovulation--like PCOS. I think that most of the women on here have taken Clomid due to ovulation problems.
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Clomid
Dec 25, 2006 21:44:20 GMT -5
Post by denna on Dec 25, 2006 21:44:20 GMT -5
hi cheryl,
i'm not sure about your gynae, mine straighaway give me clomid after i went off zoladex. thin he was thinking to put me on clomid first for 1-2 months only after that to do clomid and iui but being very proactive..not sure if this is good or not i met another gyne who do the iui straighaway..if it doesn't work after 3 rounds, they suggest i do ivf..ivf cost a lot of money...so i really don't care if clomid will do the work or not as i'm so very sure if i have ovulation problem but that the best i an do before ivf. private hopsital will sure ask you to do ivf as it brings them a lot of money ..that what i think..you can still decide on your own as it's your own body and you are paying for it.
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apple
Full Member
Posts: 214
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Clomid
Dec 27, 2006 11:37:44 GMT -5
Post by apple on Dec 27, 2006 11:37:44 GMT -5
Hi, I have stage 4 endo and my gyne and fertility specialist both agreed that the only feasible option for me (according to my history) will be IVF, my gyne said that He was quite sure I do not have ovulation problems so he was not positive on giving me Clomid or any other staff to help ovulation. Similar answers as cheryl got.
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Clomid
Dec 27, 2006 20:00:26 GMT -5
Post by akcheryl on Dec 27, 2006 20:00:26 GMT -5
Yeah, I would definitely think that the doctors were just trying to make lots of $$$ if they were pushing IVF at their own hospital, but the doctors I've spoken to don't have any direct financial benefit themselves from me getting IVF. My OBGYNs and other docs are all at different hospitals/clinics altogether (even in different states) than the fertility clinic I'm going to go to.
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Clomid
Dec 27, 2006 20:52:38 GMT -5
Post by ouchy on Dec 27, 2006 20:52:38 GMT -5
w/ IVF don't they give you injectibles to increase follicle number--same thing Clomid does, but injectible?
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Clomid
Dec 28, 2006 21:59:57 GMT -5
Post by akcheryl on Dec 28, 2006 21:59:57 GMT -5
From what I understand, Clomid induces ovulation, but it doesn't necessarily induce multiple ovulations (output of more than one egg). Clomid can, in some but not all cases, cause multiple eggs to be released, but that's not what the aim of the drug is. In in vitro fertilization, drugs are given to purposefully make the ovaries develop multiple follicles. Gonadotropins (the two main ones being FSH and LH) are injected during this step of IVF. Also, endogenous ovulation is blocked by GnRH agonists or GnRH antagonists so that the eggs can be retrieved directly from the ovaries (under normal ovulation, the ovaries would be stimulated to develop a single follicle which would rupture and discharge an egg at ovulation, but in IVF the rupturing step is blocked). In IVF, the hormones are given to stimulate the development of multiple follicles so that more than one egg can be harvested and fertilized outside the woman's body. This is so the fertility doctor can implant multiple (usually 2 to 4) embryos into the woman's uterus, thus increases her chances of achieving at least a single pregnancy. After the follicles are deemed mature, human chorionic gonadotropin (â-hCG) is administered via injection to induce ovulation. However, the eggs are harvested directly from the ovaries before the â-hCG goes into effect (it takes 36 hours for the drug to work). (Thus the woman ovulates via artificial stimulation AFTER the eggs have already been harvested using an ultrasound-guided transvaginal needle.) From what I gather, the main differences are that Clomid induces ovulation (the developement of a follicle that bursts and releases an egg) in situations where there is anovulation (due to a disease process such as PCOS), whereas IVF injections purposefully cause multiple follicle development. Clomid is not used to increase the output of eggs, it's used to counter anovulation. However, one side effect to Clomid is that it sometimes causes more than one egg to be released. Also, there are three main classes of ovarian-stimulation drugs: en.wikipedia.org/wiki/Fertility_drug
Classification
Agents that enhance ovarian activity can be classified as follows.
1. Gonadotropin releasing hormone a. GnRH b. GnRH agonists (i.e.Lupron ®) 2. Estrogen antagonists a. Clomiphene citrate (actually a SERM) b. Aromatase inhibitors 3. Gonadotropins a. Urinary gonadotropins (menotropins) i. Pergonal ® ii. Prurified menotropins (Bravelle ®, Menopur ®) b. Recombinant gonadotropins i. Follicle-stimulating hormone (Follistim ®, Gonal F ®) ii. Luteinizing hormone (Luveris ®) c. Human chorionic gonadotropin (hCG) i. Urinary hCG (Profasi ®, Novadrel ®) ii. Recombinant hCG (Ovidrel ®) It looks like Clomid falls under #2, and the IVF drugs under #3.
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Clomid
Dec 28, 2006 22:20:58 GMT -5
Post by ouchy on Dec 28, 2006 22:20:58 GMT -5
I went w/ my friend to her reproductive endocrinologist meeting, and the doctor said that Clomid often causes multiple follicles to develop and even showed a display of what a typical Clomid-treatment ovary looks like (w/ multiple follicles). It could depend on the milligrams that are taken, tough. It would make sense that the more milligrams given, the more GnRH would be produced, triggering a greater response form the pituitary to produce more FSH, potentially leading to more follicles being produced. That is why they started my friend at the lowest dose possible--so she would hopefully not pop out twins.
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Clomid
Jan 11, 2007 0:52:29 GMT -5
Post by denna on Jan 11, 2007 0:52:29 GMT -5
but i wanted twins..hehe..actually it's true so lower dose is the best
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Clomid
Jan 11, 2007 0:58:57 GMT -5
Post by ouchy on Jan 11, 2007 0:58:57 GMT -5
^So did she! One cycle she skipped her clomid and doubled-up the next month. She didn't get preg., though!
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Clomid
Jan 11, 2007 1:33:10 GMT -5
Post by denna on Jan 11, 2007 1:33:10 GMT -5
keep on trying...some ppl get it the 6th round...
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Clomid
May 4, 2007 22:37:06 GMT -5
Post by ouchy on May 4, 2007 22:37:06 GMT -5
Posted by member tiff in another thread: _________________________________________________ "I took clomid and did get pregnant! If anyone has any questions I am more than willing to answer them. If you would like you can PM me! "
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Clomid
May 7, 2007 14:45:44 GMT -5
Post by zzerebecki on May 7, 2007 14:45:44 GMT -5
i am the same as ouchy i took clomid and was lucky enough to fal pregnant. but i do have ovulation problems!
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Clomid
May 7, 2007 14:46:53 GMT -5
Post by ouchy on May 7, 2007 14:46:53 GMT -5
I've never taken clomid. I was copying/pasting a post by another member in another thread.
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Clomid
May 7, 2007 18:58:05 GMT -5
Post by Tiff on May 7, 2007 18:58:05 GMT -5
I had ovulation problems due to my 3 month round of Lupron. I took clomid for 1 month and got pregnant. I was the one who Ouchy was posting for about PM me if any one has any questions!
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Clomid
May 7, 2007 19:19:47 GMT -5
Post by ouchy on May 7, 2007 19:19:47 GMT -5
Tiff, did you ever have ovulation problems/irregular periods before you went on Lupron (and not on the b.c. pill)? I know ovulation problems are common with blood sugar issues like you and I have. Or did you chart your cycles back then? This stuff is all so interesting to me!
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